The Helltide event is one of Diablo IV gold the best opportunities to collect Horadric Vials. These timed events take over regions of the map and increase both the difficulty and rewards found there. Here’s how you can maximize vial farming during Helltides:

Collect Anomalous Embers: Use these special materials to unlock Helltide chests, which often contain Horadric Vials and other valuable loot.

Raise Threat: The more activities you complete within a Helltide, the higher your personal threat level grows. This eventually causes elite enemies and minibosses to spawn more frequently—perfect targets for vial drops.

Summon the Bloody Maiden: Using Baneful Hearts, you can summon this powerful elite boss. Defeating her gives you a great chance of earning multiple Horadric Vials in a single fight.

Complete Grim Favors for the Tree of Whispers
Grim Favors are mini-objectives that you complete in different regions. Once you collect 10, you can return to the Tree of Whispers for a D4 Gold for sale cache that often includes Horadric Vials. This method is highly recommended for players at all levels, especially when other major events are not active.